α-Endorphin
Original price was: $338.00.$99.00Current price is: $99.00.
α-Endorphin (also known as alpha-endorphin or LPH(61-76)) is an endogenous opioid peptide naturally produced in the pituitary gland and central nervous system. This 16-amino acid peptide plays a significant role in pain modulation, stress response, and emotional regulation.
α-Endorphin is a valuable tool in neuroscience research, allowing scientists to study:
- Endogenous opioid system: The body’s natural pain management and stress response mechanisms.
- Pain pathways: Understanding the neurochemical processes underlying pain perception.
- Stress response: Investigating the role of opioids in coping with stress.
- Reward systems: Exploring the involvement of opioids in reward and motivation.
Availability: In stock
Overview
α-Endorphin (also known as alpha-endorphin or LPH(61-76)) is an endogenous opioid peptide naturally produced in the pituitary gland and central nervous system. This 16-amino acid peptide plays a significant role in pain modulation, stress response, and emotional regulation.
Molecular Properties
- CAS Number: 59004-96-5
- Molecular Weight: 1745.95
- Molecular Formula: C₇₇H₁₂₀N₁₈O₂₆S
- Purity: ≥97%
Mechanism of Action
α-Endorphin exerts its effects by binding to mu, delta, and kappa opioid receptors throughout the nervous system. This binding activates inhibitory G-proteins, leading to a cascade of events:
- Reduced cAMP levels: Decreased levels of cyclic adenosine monophosphate.
- Calcium channel closure: Reduced influx of calcium ions into neurons.
- Potassium channel opening: Increased efflux of potassium ions from neurons.
These changes result in decreased neurotransmitter release, ultimately modulating pain perception and emotional responses.
Research Applications
α-Endorphin is a valuable tool in neuroscience research, allowing scientists to study:
- Endogenous opioid system: The body’s natural pain management and stress response mechanisms.
- Pain pathways: Understanding the neurochemical processes underlying pain perception.
- Stress response: Investigating the role of opioids in coping with stress.
- Reward systems: Exploring the involvement of opioids in reward and motivation.
Research with α-endorphin contributes significantly to advancements in neurobiology and endocrinology, enhancing our understanding of the body’s natural homeostasis and stress management capabilities.
Conclusion
α-Endorphin’s role as an endogenous opioid peptide is crucial to the body’s natural pain management and stress response systems. Further research using α-endorphin continues to unlock valuable insights into these complex biological processes.
Disclaimer:
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.
| Weight | 1 oz |
|---|---|
| Size | 10 MG |
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