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Palmitoyl Hexapeptide-12 (Biopeptide El™)

Price range: $79.00 through $517.00

Palmitoyl Hexapeptide-12, also known as Biopeptide El™, is a conjugate of palmitic acid and a peptide with the sequence Val-Gly-Val-Ala-Pro-Gly. This sequence is a fragment of elastin, known as the “spring fragment,” which is highly repeated in the elastin protein. It plays a vital role in boosting the production of collagen, elastin, fibronectin, and glycosaminoglycans (GAGs), key components of the skin’s extracellular matrix (ECM).

Key Benefits

  • Boosts Collagen and Elastin: Stimulates fibroblasts to increase collagen, elastin, and ECM components for firmer, more elastic skin.
  • Reduces Signs of Aging: Improves skin tone, texture, and reduces fine lines and wrinkles.
  • Enhances Hydration: Supports skin moisturization for a plump and smooth appearance.
  • Restructures and Firms Skin: Strengthens the skin’s architecture, especially on the neck and face.
  • Promotes Skin Healing: Attracts fibroblasts to repair and rejuvenate damaged or inflamed areas.
  • Synergistic with Ceramides: Works with Ceramide NG (as in Dermaxyl™) to amplify anti-aging and hydrating effects.

What is Palmitoyl Hexapeptide-12?

Palmitoyl Hexapeptide-12, also known as Biopeptide El™, is a conjugate of palmitic acid and a peptide with the sequence Val-Gly-Val-Ala-Pro-Gly. This sequence is a fragment of elastin, known as the “spring fragment,” which is highly repeated in the elastin protein. It plays a vital role in boosting the production of collagen, elastin, fibronectin, and glycosaminoglycans (GAGs), key components of the skin’s extracellular matrix (ECM).


How Palmitoyl Hexapeptide-12 Works

  1. Enhanced Delivery with Palmitic Acid:
    The attachment of palmitic acid to the hexapeptide creates a more lipophilic structure, improving its skin penetration and bioactivity. This allows the peptide to reach deeper layers of the skin for effective results.
  2. Elastin Fragment Function:
    The peptide sequence mimics elastin’s “spring fragment,” stimulating fibroblasts to produce collagen, elastin, and GAGs, which contribute to skin’s firmness, elasticity, and hydration.
  3. Chemotactic Properties:
    Palmitoyl Hexapeptide-12 has a chemotactic effect, attracting fibroblasts to sites of inflammation or damage, promoting healing and rejuvenation.
  4. Restructuring Effect:
    Biopeptide El™ strengthens the skin structure, improving firmness, tone, and moisture levels.
  5. Synergy with Ceramide NG (Dermaxyl™):
    Research shows that combining Palmitoyl Hexapeptide-12 with Ceramide NG enhances anti-aging effects, improves skin barrier function, and increases hydration.

Key Benefits

  • Boosts Collagen and Elastin: Stimulates fibroblasts to increase collagen, elastin, and ECM components for firmer, more elastic skin.
  • Reduces Signs of Aging: Improves skin tone, texture, and reduces fine lines and wrinkles.
  • Enhances Hydration: Supports skin moisturization for a plump and smooth appearance.
  • Restructures and Firms Skin: Strengthens the skin’s architecture, especially on the neck and face.
  • Promotes Skin Healing: Attracts fibroblasts to repair and rejuvenate damaged or inflamed areas.
  • Synergistic with Ceramides: Works with Ceramide NG (as in Dermaxyl™) to amplify anti-aging and hydrating effects.

Applications

Palmitoyl Hexapeptide-12 is ideal for use in:

  • Anti-aging creams and serums
  • Skin firming and toning products
  • Hydrating and moisturizing formulations
  • Neck and décolleté treatments
  • Advanced skin repair products

Functions

  • Firming
  • Anti-aging
  • Skin Conditioning

Technical Information

  • CAS Number(s): 171263-26-6
  • Molecular Formula: C38H68N6O8
  • Molecular Weight: 737.0 g/mol
  • CAS Number: 171263-26-6
  • Sequence: Pal-Val-Gly-Val-Ala-Pro-Gly (pal-VGVAPG)
  • FDA UNII: HO4ZT5S86C

Why Choose Palmitoyl Hexapeptide-12 (Biopeptide El™)?

Palmitoyl Hexapeptide-12 is a scientifically backed, multi-functional peptide that offers powerful anti-aging, firming, and hydrating benefits. Its ability to stimulate collagen, elastin, and ECM production makes it a vital ingredient in high-performance skincare products targeting aging and sagging skin.

Disclaimer:

All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.

Weight 2 oz
Size

1 G, 100 MG

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