Acetyl Hexapeptide-8 (Argireline®)
Price range: $97.00 through $677.20
Acetyl Hexapeptide-8, commonly known as Argireline®, is a powerful topical peptide developed to reduce the appearance of fine lines and expression wrinkles. Often referred to as the “Botox in a bottle”, this ingredient offers a non-invasive solution for aging skin.
Key Benefits:
- Reduces Wrinkle Depth: Clinical trials show a 27% reduction in periorbital wrinkle depth after just 30 days of twice-daily application.
- Minimizes Facial Muscle Movement: Argireline works by interfering with the SNARE complex formation, inhibiting the release of neurotransmitters responsible for muscle contraction.
- Enhances Skin Smoothness & Radiance: Fewer contractions mean smoother, firmer skin over time.
- Synergistic Effect with Leuphasyl®: When combined with Leuphasyl®, Argireline enhances anti-wrinkle efficacy. A study using 5% Argireline® and 5% Leuphasyl® solutions showed up to 46.53% wrinkle reduction.
Acetyl Hexapeptide-8 (Argireline®) | Advanced Anti-Aging Peptide for Wrinkles & Fine Lines
Product Overview:
Acetyl Hexapeptide-8, commonly known as Argireline®, is a powerful topical peptide developed to reduce the appearance of fine lines and expression wrinkles. Often referred to as the “Botox in a bottle”, this ingredient offers a non-invasive solution for aging skin.
Key Benefits: Best Anti-Aging Peptide Argireline Benefits
● Reduces Wrinkle Depth: Clinical trials show a 27% reduction in periorbital wrinkle depth after just 30 days of twice-daily application.
● Minimizes Facial Muscle Movement
● Enhances Skin Smoothness & Radiance: Fewer contractions mean smoother, firmer skin over time.
● Synergistic Effect with Leuphasyl®: When combined with Leuphasyl®, Argireline enhances anti-wrinkle efficacy. A study using 5% Argireline® and 5% Leuphasyl® solutions showed up to 46.53% wrinkle reduction.
How Argireline Works
Acetyl Hexapeptide-8 (Argireline) mimics SNAP-25 and competes within the SNARE complex to block acetylcholine release. By preventing full SNARE complex formation, it gently inhibits neurotransmitters to relax facial muscles, offering a safe, topical, non-invasive alternative to injectables for reducing expression wrinkles.
Argireline vs Botox for Wrinkle Reduction
While Botox® requires injection and clinical administration, Argireline offers a topical alternative with similar effects relaxing muscle tension and reducing the depth of expression lines. Both target the same biological mechanism, but Argireline is suitable for daily home use and compatible with other skincare actives.
Product Specifications
● INCI Name: Acetyl Hexapeptide-8
● Synonym: Argireline®
● Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
● Molecular Formula: C34H60N14O12S
● Molecular Weight: 888.99 g/mol
● CAS #: 616204-22-9
Ideal For:
● Anti-aging skincare routines
● Wrinkle-reducing creams and serums
● Formulations targeting crow’s feet and expression lines
● Peptide-based cosmetic actives
● Sensitive and all skin types
Usage Recommendation:
For cosmetic use only. Add to serums, creams, or lotions up to 5% concentration. Avoid injecting or ingesting.
Why Choose This Product?
If you want the best anti-aging peptide, then consider the Argireline peptide for wrinkles.
With clinically proven effectiveness, it is a smart choice for formulators, skincare professionals, and enthusiasts.
Disclaimer:
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.
| Weight | 2 oz |
|---|---|
| Size | 1 G, 100 MG |
| View COA | Click here |
| View MSDS | Click here |
[1] Topical peptides as cosmeceuticals
Author(s): Pai VV, Bhandari P, Shukla P
PMID:27451932 DOI:10.4103/0378-6323.186500
[2] Argireline: Needle-Free Botox as Analytical Challenge
Author(s): Kluczyk A, Ludwiczak J, Modzel M, Kuczer M, Cebrat M, Biernat M, Bąchor R
PMID:33482052 DOI:10.1002/cbdv.202000992
[3] The anti-wrinkle efficacy of Argireline
Author(s): Wang Y, Wang M, Xiao XS, Huo J, Zhang WD
PMID:23464592 DOI:10.3109/14764172.2013.769273
[4] Chemical and biological properties of anti-wrinkle peptide Argireline
Author(s): Alicja Kluczyk, Julita Ludwiczak, Maciej Modzel, Mariola Kuczer, Marek Cebrat, Monika Biernat, Remigiusz Bąchor
DOI:10.52336/acm.2021.10.3.05
[5] Small peptides patterned after the N-terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis
Author(s): Blanes-Mira C, Merino JM, Valera E, Fernández-Ballester G, Gutiérrez LM, Viniegra S, Pérez-Payá E, Ferrer-Montiel A
PMID:14675156 DOI:10.1046/j.1471-4159.2003.02133.x
[6] Investigating the effects of Argireline in a skin serum containing hyaluronic acids on skin surface wrinkles using the Visia® Complexion Analysis camera system for objective skin analysis
Author(s): Henseler H
PMID:38024099 DOI:10.3205/iprs000179
[7] Safety Assessment of Acetyl Hexapeptide-8 Amide as Used in Cosmetics
Author(s): Johnson W, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD, Liebler DC, Marks JG, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, Heldreth B
PMID:40673537 DOI:10.1177/10915818251340391
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