Dipeptide Diaminobutyroyl Benzylamide Diacetate (SYN-AKE®)

What is SYN-AKE®?

SYN-AKE® is a synthetic tripeptide that mimics Waglerin-1, a peptide found in the venom of the Temple Viper. This biomimetic compound is engineered to reduce muscle contractions, softening dynamic facial lines—particularly on the forehead, around the eyes, and mouth. It is a popular Botox alternative in non-invasive skincare.

Key Features & Benefits

• SYN-AKE peptide Botox alternative: Offers wrinkle-smoothing benefits similar to Botox without needles or clinical procedures.
• Muscle Relaxation Effect: Temporarily inhibits micro-contractions by deactivating mnACh receptors, reducing wrinkle depth by up to 52% in 28 days (in vivo study).
• SYN-AKE anti-wrinkle cream benefits: Helps firm sagging skin and smooth expression lines, making it ideal for creams, serums, and moisturizers.
• Youthful Appearance: Delivers fast, visible anti-aging results without affecting natural facial expressiveness.
• Dipeptide Diaminobutyroyl uses in skincare: Commonly formulated into cleansers, facial creams, eye treatments, and firming serums.

SYN-AKE vs Argireline Peptide        

While Argireline works by inhibiting SNARE complex formation, SYN-AKE® directly mimics neurotoxic activity to suppress muscle contractions. SYN-AKE is particularly effective for expression wrinkles and sagging skin, while Argireline is best for early-stage fine lines.

Product Details

• INCI Name: Dipeptide Diaminobutyroyl Benzylamide Diacetate
• Mechanism: Mimics snake venom peptide (Waglerin-1)
• Function: Anti-wrinkle, muscle relaxant, skin firming
• Recommended Use: 1–4% in creams, serums, and gels
• Appearance: Clear to slightly hazy liquid

Where to Buy SYN-AKE Peptide

Looking for where to buy SYN-AKE peptide? Our premium-grade SYN-AKE® is available in bulk or small quantities, perfect for formulators, skincare brands, or DIY beauty creators.