Overview
Carnosine (β-alanyl-L-histidine) is a naturally occurring dipeptide with potent antioxidant and anti-glycation properties, making it a valuable ingredient in anti-aging skincare products.
Mechanism of Action
Carnosine’s benefits stem from its ability to:
- Scavenge ROS and RCS: It neutralizes reactive oxygen and carbonyl species, protecting skin cells from oxidative stress.
- Prevent Protein Glycation: It inhibits the damaging process of glycation in the extracellular matrix (ECM), preserving the skin’s structure and function.
- React with Aldehydes: It binds to low-molecular-weight aldehydes, preventing their harmful effects on skin proteins.
- Prevent Cross-linking: It inhibits the cross-linking of macromolecules like collagen and DNA, maintaining skin firmness and elasticity.
- Chelate Heavy Metals: It acts as a chelating agent, removing harmful heavy metal ions from the skin.
- Boost Regeneration: It supports the skin’s natural regenerative processes, contributing to wound healing.
Applications
Carnosine’s versatility makes it suitable for a range of skincare applications, including anti-aging creams, serums, and wound-healing ointments (a use dating back to the 1940s).
Specifications
- Sequence: β-alanyl-L-histidine
- Molecular Formula: C₉H₁₄N₄O₃
- Molecular Weight: 226.23 g/mol
- CAS #: 305-84-0
- EINECS #: 206-169-9
- FDA UNII: 8HO6PVN24W
Functions
- Anti-aging
- Antiglycation
- Antioxidant
- Skin conditioning
Disclaimer:
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.





