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Palmitoyl Tripeptide-38

Price range: $158.00 through $1,106.00

Palmitoyl Tripeptide-38 is a synthetic lipopeptide (known as Pal-KMO2K, methionine with a dioxygenated sulfur atom) with the sequence Pal-Lys-Met(O2)-Lys. It is a matrikine-mimetic peptide that stimulates the production of more than six essential components of ECM (extracellular matrix). Sederma designed it to provide an alternative to hyaluronic acid and collagen injections while supporting an anti-aging claim.

This active ingredient provides noticeable and clinically proven filling and anti-wrinkle effects, acting on multiple skin layers such as the epidermis, the dermal-epidermal junction, and the dermis. Palmitoyl Tripeptide-38 is a multifunctional active ingredient in Sederma’s iconic complexes VoluLip™and Matrixyl™ synthe’6™, providing incredible results—pulpier lips and rejuvenated skin.

 

Palmitoyl Tripeptide-38 is a synthetic lipopeptide (known as Pal-KMO2K, methionine with a dioxygenated sulfur atom) with the sequence Pal-Lys-Met(O2)-Lys. It is a matrikine-mimetic peptide that stimulates the production of more than six essential components of ECM (extracellular matrix). Sederma designed it to provide an alternative to hyaluronic acid and collagen injections while supporting an anti-aging claim.

This active ingredient provides noticeable and clinically proven filling and anti-wrinkle effects, acting on multiple skin layers such as the epidermis, the dermal-epidermal junction, and the dermis. Palmitoyl Tripeptide-38 is a multifunctional active ingredient in Sederma’s iconic complexes VoluLip™and Matrixyl™ synthe’6™, providing incredible results—pulpier lips and rejuvenated skin.

In vivo and in vitro tests showed that Palmitoyl Tripeptide-38 acts on two layers of the skin:

  1. In the epidermis, it promotes the production of laminins, fibronectin, hyaluronic acid (HA), and CD44 protein (responsible for anchoring HA in ECM).
  2. In the dermis, Palmitoyl Tripeptide-38 stimulates the synthesis of collagens (I, III, and IV), fibronectin, and hyaluronic acid (HA).

In addition, this lipopeptide promotes the production of aquaporins, specialized proteins that play an essential role in water retention and distribution in the skin and other tissues. Moreover, DNA array tests showed that Palmitoyl Tripeptide-38 enhances the expression of genes responsible for the skin’s lipid barrier function, improving protection against external influences and reducing transdermal moisture loss.

Incorporated in skin and lip care applications, Palmitoyl Tripeptide-38 fights against signs of dermal aging (including fine lines and deep wrinkles), improves the condition, and minimizes skin imperfections, exposing a youthful, healthy, and radiant appearance.

Chemical Characters:

CAS#: 1447824-23-8

INCI: Palmitoyl Tripeptide-38

Sequence: Pal-Lys-Met(O2)-Lys

Formula: C33H65N5O7S

Molecular Weight:675.96 g/mol

Storage: 4~8°C, -20°C for long-term

Synonyms: Matrixyl Synthe’6Ô

See also

Disclaimer:

All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.

Weight 2 oz
Size

100 MG, 25 MG

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