What is Tetrapeptide-30?
Tetrapeptide-30 (INCI: PKEK – Pro-Lys-Glu-Lys) is a synthetic skin-active peptide derived from the KEK motif found in the natural antimicrobial polypeptide cathelicidin. This multifunctional tetrapeptide is designed to reduce hyperpigmentation, boost skin firmness, and promote cell renewal — making it an ideal ingredient for both anti-aging and skin-brightening formulations.
Key Benefits:
- Hyperpigmentation Control: Unlike standard tyrosinase inhibitors, Tetrapeptide-30 targets the upstream triggers of melanogenesis, specifically inflammatory cytokines (IL-6 and IL-8) and α-MSH production. This helps fade UV- or inflammation-induced dark spots, melasma, and post-inflammatory hyperpigmentation (PIH).
- Skin Cell Renewal: By soothing inflammation and supporting a healthy epidermal environment, Tetrapeptide-30 promotes skin cell turnover, improving tone, texture, and clarity over time.
- Skin Brightening Without Irritation: Reduces hyperchromatic age spots and evens out skin tone without triggering sensitivity. Excellent for all skin types, including sensitive, Asian, and melanated skin tones.
- Skin Firmness: While reducing pigmentation, Tetrapeptide-30 also improves skin firmness and elasticity, making it a multifunctional option for anti-aging skincare.
Applications:
- Brightening serums and creams
- Post-acne or post-laser PIH treatments
- Melasma and discoloration control formulas
- Anti-aging creams for dull, uneven skin
- Barrier-repair products for sensitive skin
Technical & Raw Material Info
- Synonyms: TEGO® Pep 4-Even, PKEK peptide
- Peptide Sequence: Pro-Lys-Glu-Lys
- Functionality: Skin brightening, anti-inflammatory, skin renewal
- FDA UNII: H9G9QJT7E2
- Solubility: Water-soluble
- Usage Rate: 1%–5% in emulsions, gels, or serums
Why Choose Tetrapeptide-30 and where to buy?
Tetrapeptide-30 is more than just a skin-brightening agent. Its smart anti-inflammatory mechanism, combined with firming and anti-aging benefits, makes it an exceptional choice for advanced multifunctional skincare. Whether you’re addressing dark spots, aging, or skin sensitivity, this peptide delivers real results without irritation.
Qualitide offers high-purity, cosmetic-grade Tetrapeptide-30 perfect for R&D, private label manufacturing, or DIY skincare.
Disclaimer:
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.






