Dipeptide-2 is a bioactive peptide composed of the amino acids Valine and Tryptophan (Val-Trp / VW). It is widely known for its role in reducing under-eye puffiness, edema, and dark circles, making it one of the best peptides for reducing dark circles and revitalizing tired-looking skin.
Dipeptide-2 for Under-Eye Bags & Puffiness
A popular ingredient in eye care, Dipeptide-2 for under-eye bags works by boosting lymphatic drainage and blood microcirculation. Its decongestant action helps reduce:
- Puffiness
- Fluid retention
- Swollen eye contours
That’s why it’s commonly found in Dipeptide-2 anti-puffiness serums and luxury eye creams like those formulated with Eyeliss™.
Skin Conditioning & Firming Benefits
Aside from its eye-targeted uses, Dipeptide-2 skin firming benefits extend to overall skin conditioning. It promotes smoother, firmer-looking skin by enhancing circulation and reducing stagnation, which can contribute to dull or loose skin in sensitive facial areas.
How It Works
Dipeptide-2 works by inhibiting Angiotensin-Converting Enzymes (ACE I & II)—key regulators of fluid volume and vascular tone. This effect helps alleviate water retention and improve nutrient flow to skin cells, which supports brighter, healthier-looking skin under the eyes.
Scientific Identity
- INCI Name: Dipeptide-2
- Sequence: L-Valyl-L-Tryptophan
- Molecular Formula: C₁₆H₂₁N₃O₃
- Molecular Weight: 303.4 g/mol
- CAS: 24587-37-9
- FDA UNII: 3G64B4AFQN
- Synonyms: N-Valyltryptophan, Valyltryptophan
Popular Formulations Featuring Dipeptide-2
- Eyeliss™ Complex: A peptide-based anti-puffiness formula in many top-rated serums
- Custom peptide eye creams for professional or DIY use
Where to Buy Dipeptide-2 Peptide
Looking for where to buy Dipeptide-2 peptide? Our high-purity version is available for individual consumers, skincare formulators, and commercial brands. Trusted for both clinical and cosmetic applications.
Functions & Benefits Summary
- Decongests under-eye area
- Reduces dark circles and puffiness
- Improves microcirculation
- Firms and smooths skin texture
- Ideal for eye care formulations
Disclaimer:
All products are sold strictly for laboratory research purposes only. Not for human or veterinary use, consumption, therapeutic, or diagnostic application. By purchasing, you confirm you are a qualified professional and legally permitted to handle these materials in compliance with all applicable laws and regulations. Misuse, resale for unauthorized purposes, or unlawful application is strictly prohibited. Qualitide disclaims all liability for improper use, handling, or regulatory non-compliance.





